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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
22.42
Human Site:
S122
Identified Species:
30.83
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S122
V
S
K
P
P
A
K
S
Q
R
P
E
E
E
V
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S122
V
S
K
P
P
A
K
S
Q
R
P
E
E
E
V
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S122
V
S
K
P
P
A
K
S
Q
R
P
E
E
E
V
Dog
Lupus familis
XP_533766
1089
122761
S122
V
S
K
P
P
A
K
S
Q
R
P
E
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
S122
V
S
K
P
P
S
K
S
Q
R
P
E
E
E
V
Rat
Rattus norvegicus
NP_446123
1093
121882
Q122
S
K
P
P
A
K
S
Q
R
P
E
E
E
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
P122
P
P
T
K
S
Q
R
P
K
E
E
V
K
S
N
Chicken
Gallus gallus
O42184
1433
161009
S126
F
T
R
P
S
K
L
S
R
K
V
L
T
E
D
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
R122
A
P
A
K
S
N
R
R
L
R
E
K
E
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
V74
N
P
H
A
N
E
M
V
T
I
P
P
T
P
T
Honey Bee
Apis mellifera
XP_394037
1326
150590
K149
S
K
E
V
E
I
C
K
E
K
N
I
H
D
Q
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
T704
A
L
V
L
N
Q
L
T
C
N
G
V
L
E
G
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
S122
P
P
S
K
P
K
K
S
L
G
K
K
L
Q
T
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
P117
R
K
K
D
A
E
H
P
E
I
A
E
K
K
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
Q98
E
N
P
S
Q
I
E
Q
K
E
E
E
A
G
S
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
100
N.A.
93.3
20
N.A.
0
20
0
13.3
N.A.
6.6
0
6.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
20
46.6
0
33.3
N.A.
6.6
26.6
13.3
33.3
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
6
6
12
24
0
0
0
0
6
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
6
0
6
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
0
0
0
0
0
0
0
0
12
12
% D
% Glu:
6
0
6
0
6
12
6
0
12
12
24
48
42
42
0
% E
% Phe:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
6
6
0
0
6
6
% G
% His:
0
0
6
0
0
0
6
0
0
0
0
0
6
0
0
% H
% Ile:
0
0
0
0
0
12
0
0
0
12
0
6
0
0
0
% I
% Lys:
0
18
36
18
0
18
36
6
12
12
6
12
12
6
12
% K
% Leu:
0
6
0
6
0
0
12
0
12
0
0
6
12
0
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% M
% Asn:
6
6
0
0
12
6
0
0
0
6
6
0
0
0
6
% N
% Pro:
12
24
12
42
36
0
0
12
0
6
36
6
0
6
0
% P
% Gln:
0
0
0
0
6
12
0
12
30
0
0
0
0
6
6
% Q
% Arg:
6
0
6
0
0
0
12
6
12
36
0
0
0
0
0
% R
% Ser:
12
30
6
6
18
6
6
42
0
0
0
0
0
6
6
% S
% Thr:
0
6
6
0
0
0
0
6
6
0
0
0
12
0
12
% T
% Val:
30
0
6
6
0
0
0
6
0
0
6
12
0
6
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _